The CryoEM High-Performance Computing service is designed to be an economical and sustainable enterprise solution for the CryoEM analysis toolchain, currently specifically for the application Cryosparc. This service sought to provide basic computing resources for CryoEM researchers to build off of, as well as, remove the need for undermanaged, individual large computing systems residing in lab spaces. Academic IT partnered with the Life Sciences Institute (LSI) to leverage their deep knowledge of running Cryosparc, as well as, integrating it into an enterprise grade on-premise acquisition workflow. This service runs in conjunction with storage solutions provided by Advanced Research Computing (ARC) and the individual labs RCP (Research Computing Package)/RCI (Research Computing Investments) allocations. Tier 1 support for Michigan Medicine Researchers is provided by the HITS Academic Computing and the maintenance and operations are handled by LSI IT. The service is rated for moderate data. Sensitive data is not permitted on CryoEM related services.

A single head node, three worker nodes and limited shared turbo storage are provided as a shared resource. The service is a limited resource provided to be a framework for labs to get started with the CryoEM analysis. This is not expected to provide all the resources for all CryoEM computing. Labs should expect to purchase additional computing resources, such as worker nodes, as their needs develop. 

The cluster can be accessed via https://glitters.lsi.umich.edu/

For first time account creation/access information view this link here: CryoEM (Cryo-Electron Microscopy) High-Performance Computing Service - How to Create an Account

For information on how to connect to the cluster: CryoEM (Cryo-Electron Microscopy) HPC - How to access Cryosparc

For information on how to transfer data to and from the cluster:  CryoEM (Cryo-Electron Microscopy) HPC - How to transfer data to/from the shared Cryosparc Volume

For information on how to create a project: CryoEM (Cryo-Electron Microscopy) HPC - How to create a new Project

For more information on using addons/additional software: CryoEM (Cryo-Electron Microscopy) High-Performance Computing Service - Additional Software 

For more information about Jobs and Memory usage: CryoEM (Cryo-Electron Microscopy) High-Performance Computing Service - Jobs and Memory

For more information regarding the Storage Options when using the CryoSPARC cluster: CryoEM (Cryo-Electron Microscopy) High-Performance Computing Service - Storage Options

For HITS Staff:

CryoEM (Cryo-Electron Microscopy) High-Performance Computing Service - Internal Landing Page

If your unable to find an answer to your question or need something in regards to this documentation feel free to send your inquiry to us via our CryoEM Intake Form.